This meatloaf sandwich is a cozy treat packed with flavor! Imagine a juicy, savory slice of meatloaf, nestled between two slices of bread, just waiting for you to take a bite.
What’s not to love? It’s like a warm hug for your taste buds! I enjoy adding a bit of ketchup or mustard on top for that extra zing. Perfect for lunch or a comfy dinner! 😋
Key Ingredients & Substitutions
Ground Beef: I like using an 80/20 blend for juicy meatloaf. If you’re looking for leaner options, try ground turkey or chicken. Just keep in mind they might need some extra seasoning or moisture to stay flavorful.
Bread Crumbs: Traditional bread crumbs hold the meatloaf together. If you’re gluten-free, use gluten-free breadcrumbs or crushed gluten-free crackers. For a twist, you can even use panko for a bit of crunch!
Onion and Garlic: Fresh onion and garlic add great flavor. If you’re in a rush, onion powder and garlic powder can work in a pinch. Still, nothing beats the taste of fresh when you have time!
Provolone Cheese: Provolone melts beautifully! If you can’t find it, Swiss or mozzarella make great substitutes. For a bit of a kick, cheddar is also a delicious option.
How Can I Make Sure My Meatloaf Stays Moist?
Keeping meatloaf moist can be tricky, but a few simple steps will help! First, avoid overmixing your meat mixture, as this can make it tough.
- Use breadcrumbs soaked in milk to add moisture and bind the ingredients without the meat getting dense.
- Don’t skip the egg; it’s key to keeping the mixture moist.
- Let the meatloaf rest after baking to redistribute juices before slicing!
What’s the Best Way to Grill My Sandwich for Maximum Crispiness?
To get that perfect golden crust on your meatloaf sandwich, follow these tips:
- Use medium heat and let the skillet warm up before adding the sandwich to avoid sogginess.
- Spread butter on the outside of the bread for a rich, crispy crust. You could use mayonnaise as a substitute for a different flavor!
- Cook slowly, flipping the sandwich gently. This ensures the cheese melts perfectly without burning the bread.
With these tips and ingredients, you’re set for a delicious and satisfying meatloaf sandwich experience! Enjoy every bite!

How to Make a Delicious Meatloaf Sandwich
Ingredients You’ll Need:
For the Meatloaf:
- 1 lb ground beef (80/20 blend)
- 1/2 cup breadcrumbs
- 1/4 cup milk
- 1/2 medium onion, finely chopped
- 1 clove garlic, minced
- 1/4 cup grated Parmesan cheese
- 1 large egg
- 1 tablespoon Worcestershire sauce
- 1 teaspoon dried oregano
- 1 teaspoon dried basil
- 1/2 teaspoon salt
- 1/2 teaspoon black pepper
- 1/3 cup ketchup (for topping the meatloaf)
For the Sandwich:
- 4 slices of good quality sandwich bread (preferably sourdough or thick-cut white)
- 4 slices of provolone cheese (or Swiss cheese)
- 2 tablespoons butter (for grilling the sandwich)
- Optional: sautéed mushrooms or caramelized onions
How Much Time Will You Need?
This meatloaf sandwich takes about 15 minutes to prepare, plus 50-60 minutes to bake the meatloaf. After that, you’ll need 10 more minutes to cool before slicing and assembling your delicious sandwich. In total, plan for around 1 hour and 30 minutes, but the wait is worth it!
Step-by-Step Instructions:
1. Preparing the Meatloaf:
First, preheat your oven to 350°F (175°C). In a large mixing bowl, combine the ground beef, breadcrumbs, milk, chopped onion, minced garlic, Parmesan cheese, egg, Worcestershire sauce, oregano, basil, salt, and pepper. Mix gently but thoroughly until all your ingredients are well blended.
2. Forming the Meatloaf:
Shape your meat mixture into a loaf that is about 8 inches long and 4 inches wide—this will fit perfectly for your sandwiches. Place the loaf on a rimmed baking sheet or in a loaf pan, then spread ketchup evenly on top.
3. Baking the Meatloaf:
Pop your meatloaf into the preheated oven and bake it for about 50-60 minutes, or until its internal temperature reaches 160°F (70°C). Once baked, let it rest for 10 minutes before slicing to keep all those delicious juices inside.
4. Assembling the Sandwich:
Now it’s time to slice your meatloaf into thick portions, roughly the same thickness as your bread slices. For each sandwich, start with one slice of bread, then layer on a piece of meatloaf. Top it with a slice of provolone cheese and, if you like, some sautéed mushrooms or caramelized onions. Add another slice of meatloaf and a second slice of cheese before finishing with another slice of bread on top.
5. Grilling the Sandwich:
Heat a skillet over medium heat. While it’s heating up, spread butter on the outer sides of the sandwich. Place the sandwich in the skillet and grill it for about 3-4 minutes per side, pressing gently with a spatula, until the bread is golden brown and the cheese has completely melted.
6. Serving:
Carefully remove your sandwich from the skillet and let it cool slightly. If you prefer, slice it in half for easier handling. Now you can dig in and enjoy your warm, cheesy meatloaf sandwich!
This meatloaf sandwich combines warm, savory flavors with crispy, buttery bread for a meal that is both filling and comforting. Enjoy every bite!
Can I Use Leftover Meatloaf for This Sandwich?
Absolutely! Leftover meatloaf works perfectly in this sandwich. Just slice it up and follow the same assembly instructions. You can reheat the slices slightly before assembling if you prefer a warm sandwich!
Can I Make This Sandwich Without Cheese?
Definitely! If you’re looking to skip the cheese for dietary reasons or personal preference, feel free to omit it. You can add extra toppings like avocado, fresh veggies, or a spread like mustard or mayo to enhance the flavor.
How Do I Store Leftover Meatloaf Sandwiches?
If you have leftovers, store the assembled sandwich in an airtight container in the fridge for up to 2 days. To keep the bread from getting soggy, it’s best to store the meatloaf and bread separately and assemble them again before serving.
Can I Freeze Meatloaf for Future Sandwiches?
Yes, you can freeze the meatloaf! Once it’s cooked and cooled, wrap it tightly in plastic wrap and then in aluminum foil, or place it in an airtight freezer bag. It can last for up to 3 months in the freezer. Thaw in the fridge before using for your sandwiches!



